Nasrin Hooshmand – Nanoplasmonics

Selected Peer-Reviewed Publications

Journal papers:

M. logoa, A Jalihala, N. Hooshmand, M. Zubairc, S. Jenkinsd, N. Alwana, M. El-Sayed, N. Alic, R. J. Griffind and N. Siraj, Enhanced photothermal heating and combination therapy of NIR dye via conversion to self-assembled ionic nanomaterials, Journal of Materials Chemistry B, 2022, 10, 806-816.
N. Hooshmand, A. Thoutam, M. Anikovskiy, H. I. Labouta, M.A. El-Sayed, Localized surface plasmon resonance as a tool to study protein corona formation on nanoparticles, Journal of Physical Chemistry C, 2021, 125, 45, 24765–24776.
Nishikiori, Y.Kageshima, N.Hooshmand, M.A. El-Sayed, K. Teshima, Observation of Excited State Proton Transfer between the Titania Surface and Dye Molecule by Time-Resolved Fluorescence Spectroscopy, Journal of Physical Chemistry C, 2021.
M. S. Ali, N. Hooshmand, M. A. El-Sayed, H. I. Labouta, Microfluidics for Development of Lipid Nanoparticles: Paving the Way of Nucleic acids to the Clinic, ACS Applied Bio Materials, 2021.
Deinavizadeh, A.R. Kiasat, N. Hooshmand*, M. Shafiei, M. Sabaeian, R. Mirzajani, S. M. Zahraei, H. I. Labouta, M. A. El-Sayed, Smart NIR-light and pH responsive doxorubicin-loaded GNRs@SBA-15-SH nanocomposite for chemo-photothermal therapy of cancer, Nanophotonics, DOI: 10.1515/nanoph-2021-0207.
Hooshmand* , Hagar I. Labouta , Tushar Upreti, Mostafa A. El-Sayed, Localized Plasmonic Photothermal Therapy as a Life-Saving Treatment Paradigm for Hospitalized COVID-19 Patients, Plasmonics, 16, 2021, 1029-1033.
Nishikiori, H. Kondo, Y. Kageshima, N. Hooshmand, S. R Panikkanvalappil, D. A Valverde-Chavez, C. Silva, M. A El-Sayed, K. Teshima, Observation of photoinduced proton transfer between the titania surface and dye moleculethe, Journal of Physical Chemistry C , 124, 7, 2020, 4172–4178.
Sharifi, S. H. Hosseinali, R. H. Alizadeh, A. Hasan, F. Attar, A. Salihi, M. S. Shekha, K. M. Amen, F.M. Aziz, A. A. Saboury, K. Akhtari, A. Taghizadeh, Hooshmand, M. A. El-Sayed, M. Falahati,Plasmonic and chiroplasmonic nanobiosensors based on gold nanoparticles, Talanta, 212, 2020, 120782 .
Falahati, F. Attar, M. Sharifi, A.A. Saboury, A. Salihi, F.M. Aziz, I. Kostova, C. Burda, P. Priecel, J. A. Lopez-Sanchez; S. Laurent; N. Hooshmand, M. A. El-Sayed “Gold nanomaterials as key suppliers in biological and chemical sensing, catalysis, and medicine” Biochimica et Biophysica Acta (BBA) – General Subjects, 1864 (1), 2020, 129435.
Hooshmand and Mostafa El-Sayed, Collective multipole oscillations direct the plasmonic coupling at the nanojunction interfaces, Proceedings of the National Academy of Sciences, 116, 2019, 19299-19304.
Sharifi, F. Attar, A. A. Saboury, K. Akhtari, N. Hooshmand, A. Hasan, M. A. El-Sayed, M. Falahati, Plasmonic gold nanoparticles: Optical manipulation, imaging, drug delivery, and therapy” , Journal of Controlled Release, 311, 2019,170-189.
Panikkanvalappil, C. Garlapati, N. Hooshmand, R.Aneja, and M.A.El-Sayed, Monitoring the dynamics of hemeoxygenase-1 activation in head and neck cancer cells in real-time using plasmonically enhanced Raman spectroscopy, Chemical Science, 10, 2019, 4876–4882.
Feghhi, R. Malakooti, S. Malakooti, and N. Hooshmand, Easy scale up synthesis of Mo₈O₂₆(C₅H₆N)4.H₂O hybrid with rectangular prism morphology: as an efficient and highly recyclable bi-functional catalyst for Knoevenagel condensation and aerobic oxidation” ChemistrySelect, 4 (9), 2019, 2551-2561.
Hooshmand, H. Mousavi, S. R. Panikkanvalappil, M. A. El-Sayed and A. Adibi, High-sensitivity molecular sensing using plasmonic nanocube chains in classical and quantum coupling regimes, Nano Today, 17, 2017, 14-22.
R. Panikkanvalappil, N. Hooshmand, and M. A. El-Sayed, Intracellular assembly of nuclear-targeted gold nanosphere enables selective plasmonic photothermal therapy of cancer by shifting their absorption wavelength toward near-infrared region, Bioconjugate Chemistry, 28 (9), 2017, 2452–2460.
Hooshmand, S. R. Panikkanvalappil, and M. A. El-Sayed, Effects of the substrate refractive index, the exciting light propagation direction, and the relative cube orientation on the plasmonic coupling behavior of two silver nanocubes at different separations, Journal of Physical Chemistry C,120 (37), 2016, 20896–20904.
Hooshmand, J. A. Bordley, and M. A. El-Sayed, The sensitivity of the distance dependent plasmonic coupling between two nanocubes to their orientation: edge-to-edge vs face-to-face, Journal of Physical Chemistry C, 120 (8), 2016, 4564–4570.
Hooshmand, J. A. Bordley and M. A. El-Sayed, Plasmonic spectroscopy: the electromagnetic field strength and its distribution determine the sensitivity factor of face-to-face Ag nanocubes dimers in solution and on a substrate, Journal of Physical Chemistry C,119 (27), 2015, 15579–15587.
A. Bordley, N. Hooshmand, and M. A. El-Sayed, Near-field coupling between gold and silver homo-nanocube dimers: the near touching coupling region, Nano Letters, 15 (5), 2015, 3391–3397.
Hooshmand, D. O’Neil, and M. A. El-Sayed, Spectroscopy of homo and heterodimers of silver and gold nanocubes as a function of separation: a DDA simulation, Journal of Physical Chemistry A, 118 (37), 2014, 8338–8344.
Hooshmand, J. A. Bordley, and M. A. El-Sayed Are hot spots between two plasmonic nanocubes of silver or gold formed between adjacent corners or adjacent facets? A DDA examination, Journal of Physical Chemistry Letters, 5 (13), 2014, 2229-2234.
Khalighyan, N. Hooshmand, N. Razzaghi-Asl, K. Zare and R. Miri, Response surface strategy in the synthesis of Fe3O4 nanoparticles, International Journal of Nano Dimension, 5(5), 2014, 421-430, 2008-8868.
Monajjemi, N. Hooshmand and F. Mollamin, NMR shielding and thermodynamic density functional theory (DFT) studies of solvent effect on B₁₀N₁₁H₇(Ala)₂ nanocone, African Journal of Microbiology Research, 6(20), 2012, 42.
Hooshmand, P. K. Jain, and M. A. El-Sayed, Plasmonic spheroidal metal nanoshells showing larger tunability and stronger near fields than their spherical counterparts: an effect of enhanced plasmon coupling, Journal of Physical Chemistry Letters,2(5), 2011, 374-378.
Monajjemi, N. Hooshmand and F. Mollamin, Molecular dynamics, Monte Carlo and DFT studies of Boron-Nitride nanocones: properties investigating B₁₀N₁₁H₇(Thr)₂ in different temperatures and solvents, Journal of Medicinal Plants Research, 5(11), 2011, 2289-2297.

Invited book chapters:

Hooshmand, Plasmonic field distribution of homo- and hetero dimeric silver and gold nanoparticles, in nanoplasmonics – fundamentals and applications; Barbillon, G., Ed.; InTech: Rijeka, 20 17, DOI: 10.5772/67411 10.5772/67411.
Hooshmand, Plasmonic properties of two silver nanocubes: dependence on separation distance, relative orientation, refractive index of the substrate, and exciting light propagation direction, in frontiers of plasmon enhanced spectroscopy, Volume 2; Itoh, T.; Graham, D.; Ozaki, Y.; Schatz, G. C., Eds.; American Chemical Society, 2016; Vol. 1246.

Invited Talks

Plasmonic nanoparticles for sensing, drug delivery and photothermal therapy of cancer, the Minerals, Metals & Materials Society (TMS), Anaheim, CA, Feb, 2022.
The unique world of metallic nanoparticles, ACS – Undergraduate Research Symposium, Mid-Hudson College, NY, (Keynote speaker) 2021.
Engineered Plasmonic Nanoparticle Based Detection: Advanced Sensitivity and Selectivity, The Minerals, Metals & Materials Society (TMS) , Orlando, FL, Mar, 2021.
Metallic nanoparticle assemblies for tunable nanoscale sensors, The Minerals, Metals & Materials Society (TMS) , San Diego, CA, Feb, 2020, (Session Chair for functional nanomaterials 2020: translating innovation into pioneering technologies: translating innovation into pioneering technologies).
Engineered nanoparticles for sensing, NANO Boston Conference (NWC Boston) Boston, MA, Apr 2020.
Exploring novel routes to design ultrasensitive sensors through developing nanotparticle-based sensor “American Chemical Society’s 2019 Southwest Regional and Rocky Mountain Regional Meeting “El Paso, TX, Nov 2019.
Plasmonic assemblies of gold and silver nanoparticles exhibit high detection sensitivity at the nanoscale plasmonic coupling regime “70th South Eastern Regional Meeting of the American Chemical Society “Augusta, GA, Nov 2018.
Using the DDA method to determine the plasmonic coupling behavior between a pair of Ag nanocubs of different orientations, separations, and media of different dielectric functions, Renewable and sustainable energy institute (RASEI)” University of Colorado, Boulder” Mar 2016.

Seminars

Engineered nanoparticles for bio-sensing and photothermal therapy of cancer, Clark Atlanta University, Atlanta GA, Jan 2020.
Collective plasmonic coupling of silver or gold nanoparticles for advanced sensing, the University of Texas at Dallas, 2020.
Nanoparticles Arrays Made of Ag and Au, Exhibit High Detection Sensitivity at Plasmonic Coupling Regime: Dependence on Different Assembly Parameters” University at Buffalo, the State University of New York, Buffalo, NY” Sept 2018.
Plasmonic properties of single and dimer of Ag nanocubes: DDA examination, nanoBIO NODE Site Visit” University of Illinois, Urbana–Champaign” Apr 2016.

Selected Technical Conference Presentations

The Effect of Gold Nanoparticle Protein corona formation on its imaging capability of tumor tissue, 7th FIP Pharmaceutical Sciences World Congress (PSWC2020), Montreal, Canada, May 2020.
In-Situ investigation of organic additive interactions in copper electroplating solutions with surface-enhanced Raman spectroscopy (SERS), 2019 IEEE 69th Electronic Components and Technology Conference (ECTC), DOI: 10.1109/ECTC.2019.00244.
Collective multipole oscillations direct the plasmonic coupling at the nano junction interfaces, 93rd ACS Colloid & Surface Science Symposium, Atlanta, GA, June 2019.
Plasmonic nanoparticles made of Ag and au, exhibit high detection sensitivity, Gordon Research Conference on harvesting, generating, and manipulating light at the nanoscale, Newry, ME, July 2018.
Dependence of the plasmonic properties of two silver nanocubes on their separation, relative orientation, refractive index of the substrate and propagation direction of the exciting light, 253rd ACS National Meeting, San Francisco, CA, Apr 2017.
Sensing the power of two nanoparticles at near sub-nanometer, in different orientations, 251st American Chemical Society National Meeting & Exposition, San Diego, CA, Mar 2016.
Where do the hot spots between two plasmonic nanocubes of silver or gold form: between adjacent corners or adjacent facets? A DDA examination, 2015 MRS Meeting &Exhibit, San Francisco CA, Apr 2015.
Effect of the exciting light polarization direction, separation distance, and the metal type on the plasmonic coupling between homo- and hetero-cubic pairs of metallic silver and gold, 247th ACS National Meeting & Exposition, Dallas, TX, Mar 2014.
Studies of the plasmonic coupling in three different pairs of solid cubes with sharp corners, Au/Au, Ag/Ag and Au/Ag; a method for tuning plasmonic properties, ACS Southeastern Regional Atlanta, GA, Nov 2013.

Nasrin Hooshmand is a Principal Research Scientist in the School of Chemistry & Biochemistry. Her research interests center on light-matter interaction at the nanoscale particularly to develop novel solutions for chemical and biological sensing, energy, nanomedicine, and healthcare applications. She has developed theories of the structure of localized strong electromagnetic fields (hot spots) generated between neighboring silver and gold nanoparticles at nanoscale separation distances. These nanoparticles can be used in surface-enhanced spectroscopy to design more sensitive optical sensors, which have many applications including single-molecule spectroscopy, biomedical, and ultrafast optoelectronic applications. Areas of research include:

Nanoparticle synthesis, characterization, and delivery to develop novel solutions for biomedical, sensing, energy, nano-optics, and healthcare applications.
Multidisciplinary research on novel nanoparticles and tailoring biomolecular interactions of nanoparticles for their cancer‐targeted drug delivery, cellular imaging, surface-enhanced Raman scattering (SERS), and plasmonic photothermal therapy (PPTT).
Studying the basics of plasmonic properties of nanoparticles approaches to engineering near and far fields, and applications in molecular sensing, nanophotonics, catalysis, and nano-optics.
Atomistic level simulations, enabling accurate in silico prediction of molecular dynamics and physiochemical properties of nanoparticles in relation to their biological function; using Molecular Dynamics (MD) simulations, density functional theory (DFT).

Core expertise:

Nanoplasmonics
Photothermal Therapy of Cancer
Nanophotonics
Surface-enhanced Raman Spectroscopy
Sensors
Nanomedicine
Drug Delivery

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